KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
13.64
Human Site:
Y754
Identified Species:
23.08
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y754
N
E
V
G
R
G
Q
Y
S
A
E
T
S
R
L
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S714
G
Q
Y
S
A
E
T
S
R
L
M
L
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
Y698
N
E
V
G
R
G
Q
Y
S
A
E
T
S
R
L
Dog
Lupus familis
XP_547004
2144
235913
Q717
V
A
S
G
R
T
N
Q
S
I
M
V
Q
W
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y736
N
Q
V
G
K
G
Q
Y
S
T
E
T
S
R
L
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y724
N
Q
V
G
K
G
Q
Y
S
T
E
T
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
N714
P
P
P
E
T
E
H
N
G
I
L
H
G
Y
N
Chicken
Gallus gallus
Q8AV58
2169
239459
M714
S
S
E
T
S
R
L
M
L
P
E
E
P
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
V710
P
E
P
Q
L
N
G
V
L
R
G
Y
V
L
R
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
P741
N
R
V
G
E
G
S
P
S
E
P
S
N
V
V
Honey Bee
Apis mellifera
XP_623565
2176
242722
V715
P
S
D
P
S
N
V
V
V
L
P
Q
E
P
P
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S740
K
H
G
P
G
K
P
S
L
P
S
Y
S
V
T
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
K751
N
A
I
G
M
S
E
K
S
E
A
S
N
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
0
100
20
N.A.
80
80
N.A.
0
6.6
N.A.
6.6
0
33.3
0
6.6
20
P-Site Similarity:
100
6.6
100
20
N.A.
93.3
93.3
N.A.
0
13.3
N.A.
6.6
0
53.3
0
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
8
0
0
0
0
15
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
22
8
8
8
15
8
0
0
15
36
8
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
50
8
36
8
0
8
0
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
8
0
0
0
15
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
8
0
22
15
8
8
0
8
29
% L
% Met:
0
0
0
0
8
0
0
8
0
0
15
0
0
0
0
% M
% Asn:
43
0
0
0
0
15
8
8
0
0
0
0
15
0
8
% N
% Pro:
22
8
15
15
0
0
8
8
0
15
15
0
15
15
8
% P
% Gln:
0
22
0
8
0
0
29
8
0
0
0
8
8
0
8
% Q
% Arg:
0
8
0
0
22
8
0
0
8
8
0
0
0
29
8
% R
% Ser:
8
15
8
8
15
8
8
15
50
0
8
15
36
0
8
% S
% Thr:
0
0
0
8
8
8
8
0
0
15
0
29
0
0
8
% T
% Val:
8
0
36
0
0
0
8
15
8
0
0
8
8
22
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
29
0
0
0
15
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _